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Special Wanring
Adverse Events Leading to Discontinuation of Treatment: - Fifteen percent of approximately 4000 patients who received fluoxetine in North American clinical trials discontinued treatment due to an adve
rse event. The more common events causing discontinuation included: Psychiatric, primarily nervousness, anxiety, and insomnia; digestive, primarily nausea; nervous system, primarily dizziness, astheni
a and headaches; skin, primarily rash and pruritus. In obsessive compulsive disorder studies, 12.1% of fluoxetine treated patients discontinued treatment early because of adverse events. Anxiety, and
rash, at incidences of less than 2%, were the most frequently reported events.
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What is this Drug
Prozac , an antidepressant (mood elevator), is used to treat depression, obsessive-compulsive disorders, and some eating disorders. Prozac (Sarafem) is used to treat premenstrual dysphoric disorder.
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What side effects can this medication cause?
Side effects from Prozac are common:
- upset stomach
- drowsiness
- weakness or tiredness
- excitement or anxiety
- insomnia
- nightmares
- dry mouth
- ski
n more sensitive to sunlight than usual
- changes in appetite or weight
Tell your doctor if any of these symptoms are severe or do not go away:
- constipation
- difficult
y urinating
- frequent urination
- blurred vision
- changes in sex drive or ability
- excessive sweating
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Symptoms of overdose
Nausea and vomiting were prominent in overdoses involving higher fluoxetine doses. Other prominent symptoms of overdose included agitation, restlessness, hypomania, and other signs of CNS excitation,
including seizures.
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Precautions
Geriatrics: - Elderly patients should initially receive fluoxetine in low dosage with slow progressive increases only if required and tolerated. Patients who have concomitant systemic illnesses or who
are receiving other drugs concomitantly should be under careful observation at all dosage levels.
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Proper Use of This Medicine
Prozac comes as a capsule, tablet, and liquid to take by mouth. It is usually taken once or twice a day and may be taken with or without food. Follow the directions on your prescription label carefull
y, and ask your doctor or pharmacist to explain any part you do not understand. Take Prozac exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Prozac oral liquid comes with a specially marked dropper for measuring the dose. Ask your pharmacist to show you how to use the dropper. Dilute the liquid in 4 ounces (120 ml) of water, apple j
uice, or Gatorade just before taking it.
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