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Other medical problems
Make sure you tell your doctor if you have any other medical problems, especially:
- Alcohol abuse or
- Drug abuse or dependence¡XDependence on butalbital may develop; also, acetaminophen ma
cause liver damage in people who abuse alcohol
- Asthma, emphysema, or other chronic lung disease or
- Hepatitis or other liver disease or
- Hyperactivity (in children) or
- Kidne
y disease¡XThe chance of serious side effects may be increased
- Diabetes mellitus (sugar diabetes) or
- Mental depression or
- Overactive thyroid or
- Porphyria¡XButalbital can ma
these conditions worse
- Heart disease (severe)¡XThe caffeine in some butalbital and acetaminophen combinations can make some kinds of heart disease worse
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What Is It
Some butalbital and acetaminophen combinations also contain caffeine (KAF-een) . Caffeine may help to relieve headaches. However, caffeine can also cause physical dependence when it is used for a long
time. This may lead to withdrawal (rebound) headaches when you stop taking it.
Butalbital and acetaminophen combination may also be used for other kinds of headaches or other kinds of pain a
s determined by your doctor.
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Other Medicines
It is especially important that your health care professional know if you are taking any of the following:
- Antidepressants, tricyclic (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendi
n], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [
e.g., Surmontil]) or
- Central nervous system (CNS) depressants (medicines that often cause drowsiness)¡XThese medicines may add to the effects of butalbital and increase the chance of drowsiness
or other side effects
- Divalproex (e.g., Depakote) or
- Valproic acid (e.g., Depakene)¡XThe chance of side effects may be increased
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How to Use
People who get a lot of headaches may need to take a different medicine to help prevent headaches. It is important that you follow your doctor's directions about taking the other medicine, even if you
r headaches continue to occur. Headache-preventing medicines may take several weeks to start working. Even after they do start working, your headaches may not go away completely. However, your headach
es should occur less often, and they should be less severe and easier to relieve than before. This will reduce the amount of headache relievers that you need. If you do not notice any improvement afte
r several weeks of headache-preventing treatment, check with your doctor.
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Symptoms of overdose
Seek emergency medical attention. Symptoms of an acetaminophen / butalbital / caffeine - Fioricet overdose include insomnia, restlessness, tremor, nausea, vomiting, diarrhea, abdominal pain, sweating,
seizures, drowsiness, decreased breathing,
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Precautions while Using this Medicine
Before you have any medical tests, tell the person in charge that you are taking this medicine. Caffeine (present in some butalbital and acetaminophen combinations) interferes with the results of cert
ain tests that use dipyridamole (e.g., Persantine) to help show how well blood is flowing to your heart. Caffeine should not be taken for 8 to 12 hours before the test. The results of other tests may
also be affected by butalbital and acetaminophen combinations.
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