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Symptoms of overdose may include:
Bloody or black, tarry stools; continuing thirst; dizziness; drowsiness ; headache, severe or continuing; nausea and/or vomiting; shortness of breath; stomach pain; sudden decrease in the amou
nt of urine; swelling of face, fingers, and/or lower legs; tightness in chest and/or wheezing; troubled breathing; unusual tiredness or weakness; vomiting of blood or material that looks like cof
fee grounds; weight gain
- lack of energy
- drowsiness
- upset stomach
- vomiting
- stomach pain
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Other Medicines
If Celebrex is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Celebrex with the
following:
- ACE-inhibitors (a type of blood pressure and heart medication, including such drugs as Capoten, Vasotec, and Prinivil)
- Blood thinning agents such as Coumadin
- Fluco
nazole (Diflucan)
- Furosemide (Lasix)
- Lithium (Eskalith, Lithobid)
- Thiazide diuretics (water pills) such as hydrochlorothiazide and Dyazide
If you take low-dose aspirin t
o protect against heart attack, you can continue taking it with Celebrex.
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What special precautions should I follow?
The presence of other medical problems may affect the use of celecoxib. Make sure you tell your doctor if you have any other medical problems, especially:
- Alcohol abuse or
- Bleeding probl
ems or
- Stomach ulcer or other stomach or intestinal problems or
- Tobacco use (or recent history of)¡XThe chance of side effects may be increased
- Anemia or
- Asthma or
- D
hydration or
- Fluid retention (swelling of feet or lower legs) or
- Heart disease or
- High blood pressure or
- Kidney disease or
- Liver disease¡XCelecoxib may make these co
ditions worse
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How should you take this medication?
Celecoxib comes as a capsule to take by mouth. It is usually taken once or twice a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any par
t you do not understand. Take celecoxib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
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What is this medicine
Celebrex is prescribed for acute pain, menstrual cramps, and the pain and inflammation of osteoarthritis and rheumatoid arthritis. It is the first of a new class of nonsteroidal anti-inflammatory drug
s (NSAIDs) called "COX-2 inhibitors." Like older NSAIDs such as Motrin and Naprosyn, Celebrex is believed to fight pain and inflammation by inhibiting the effect of a natural enzyme called COX-2. Unli
ke the older medications, however, it does not interfere with a similar substance, called COX-1, which exerts a protective effect on the lining of the stomach. Celebrex is therefore less likely to cau
se the bleeding and ulcers that sometimes accompany sustained use of the older NSAIDs.
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What side effects may occur?
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your
doctor as soon as possible if any of the following side effects occur:
- Bloody or black tarry stools; burning feeling in chest or stomach; chills; congestion in chest; cough; diarrhea; fati
gue; fever; loss of appetite; muscle aches and pains; nausea; shortness of breath; stomach pain (severe); tenderness in stomach area; unusual weight gain; vomiting of blood or material that l
ooks like coffee grounds; weakness
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