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Description
Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine.
Acyclovir is best used as soon as pos
sible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear.
If you are taking acyclovir for the treatment of chickenpox , it is best to st
art taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day.
Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an
empty stomach.
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Before Using This Medicine
Other medicines¡XAlthough certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your do
or may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) me
dicine that is to be applied to the same area of the skin.
Other medical problems¡XTell your doctor if your herpes simplex infection keeps coming back while you are using acyclovir
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Symptoms of overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include sluggishness, change in amount of urine, loss of consciousness, or se
izures.
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Other Medicines
Inform your doctor if you are taking any of the following:
- Lithium (e.g., Lithane) or
- Methotrexate or
- Other medicine for infection or
- Penicillamine (e.g., Cuprimine)
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How to Use
Take acyclovir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Use this medication as soon as possible after symptoms appear.
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What side effects can this medication cause?
Parenteral:
1. Renal toxicity; precipitation of acyclovir crystals can occur in renal tubules if the maximum solubility of free acyclovir (2.5mg/ml at 37?C in water) is exceeded or if the drug is
given by bolus injection. Serum creatinine and BUN rise and creatinine clearance decreases.
2. Encephalopathic changes: Approximately 1% of patients receiving IV acyclovir manifested encephalopath
ic changes characterized by lethargy, obtundation, tremors, confusion, hallucinations, agitation, seizures or coma.
3. Other: transient elevation of serum creatinine; rash or hives; diaphoresis; h
ematuria; hypotension; headache and nausea; thrombocytosis.
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