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Drug Interactions
Tell you doctor if you are taking any of the following:
- Deferoxamine (e.g., Desferal) (with long-term use) or
- Gold salts (medicine for arthritis) or
- Inflammation or pain medicine

Before Using This Medicine
Pregnancy¡XTopical acyclovir has not been studied in pregnant women. However, this medicine has not been shown to cause birth defects or other problems in animal studies using mice, rats, or rabbits, xcept when given in very high doses in a study using rats.

Breast-feeding¡XIt is not known whether topical acyclovir passes into the breast milk. However, acyclovir ointment has not been repo ted to cause problems in nursing babies, even though small amounts of topical acyclovir are absorbed through the mother's skin and mucous membranes. Although most medicines pass into breast milk in sm all amounts, many of them may be used safely while breast-feeding.

Precautions
Category C. Risk to fetus cannot be ruled out. Consider use if benefit outweighs the potential risk. Exposure registry is available: 1-800-722-9292, ext. 58465 (note: this number is no longer used for antiretroviral drugs. See Health Maintenance section for the pregnancy protocols which contain the antiretroviral registry number.)

Symptoms of overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include sluggishness, change in amount of urine, loss of consciousness, or se izures.

What is this Drug
Acyclovir is used to treat herpes infections of the skin, lip, and genitals; herpes zoster (shingles); and chickenpox. It does not cure herpes infections but decreases pain and itching and promotes he aling.

Topical acyclovir does not prevent the recurrence of sores but may decrease pain and itching if applied when the earliest symptoms first appear. Oral acyclovir decreases the frequency and severity of recurrent sores, but it is used only by people with severe herpes infections because of possible adverse effects.

Side Effects
This medication may cause stomach upset, loss of appetite, nausea, vomiting, diarrhea, headache, dizziness or weakness. These effects should disappear in a few days as your body adjusts to the medicat ion. If they persist or become worse, inform your doctor. Notify your doctor if you experience: numbness or tingling of the hands or feet, leg pain, sore throat, skin rash, change in the amount of uri ne. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. I f you notice other effects not listed above, contact your doctor or pharmacist.


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